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In June, the World Health Organization (WHO) released a statement to alert users about the risk of NAION associated with semaglutide medicines, citing that the frequency of the side effect is classified as very rare. The European Medicines Agency (EMA) has recommended updating the production information for the drugs to include NAION as a side effect

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The effects on weight, cardiovascular health, and other parameters of decreasing the dose or pausing and resuming the use of GLP-1 agonist is an area where evidence-based studies are needed

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